NFL Week 1 Prediction Market Odds
GAME MARKETS · PRICES LIVECompare live NFL Week 1 odds for all 16 games on the 2026 schedule. See moneyline, point spread and over/under prices from Kalshi and Polymarket US, plus win probabilities, trading volume and trade counts for every matchup from Sept. 9–14.
Market snapshot updated Sept. 5, 2026. The live board continues to update as prices and trading activity change.
With opening night less than four days away, Week 1 markets have generated approximately $180.6K across 8,032 trades. New England-Seattle leads the slate in both volume and trade count, Buffalo-Houston is separated by one percentage point, and the Los Angeles Chargers remain the week's largest favorite.
The focus now shifts to late availability updates, depth-chart decisions and whether new information produces meaningful market movement before kickoff.
What the Week 1 markets are telling us
Biggest favorite: Chargers 83% vs. Cardinals 19%
Closest game: Bills 50% vs. Texans 51%
Volume and trade-count leader: Patriots vs. Seahawks, approximately $40.6K across 1,995 trades
Opening-night favorite: Seahawks 62% vs. Patriots 39%
Week 1 volume: Approximately $180.6K across 16 games and 8,032 trades
These figures are a Sept. 5 snapshot rather than fixed forecasts. The live cards above show the newest available prices, spreads, totals, volume and trade counts.
The opening-night rematch leads Week 1 activity
The season begins Sept. 9 with New England returning to Seattle for a rematch of Super Bowl LX. The Patriots-Seahawks market currently prices Seattle at 62% and New England at 39%.
At approximately $40.6K across 1,995 trades, the matchup leads the Week 1 board in both dollar volume and trade count. That makes it the clearest place to watch for late changes before the first kickoff.
49ers-Rams ranks second in market activity
The San Francisco-Los Angeles market has generated approximately $35.8K across 1,323 trades. The Rams are priced at 65% to win the Sept. 10 game in Melbourne, compared with 37% for the 49ers.
It is the second-largest Week 1 market by both volume and trade count, well ahead of the rest of the slate outside the opener.
Bills-Texans remains the closest moneyline
The Bills-Texans market is the slate's tightest matchup after rounding, with Buffalo at 50% and Houston at 51%.
The game has generated approximately $7.6K across 462 trades. With the teams separated by one percentage point, even a modest shift in late-week expectations could change the favorite.
The Chargers and Jaguars are the largest favorites
The Chargers-Cardinals market gives Los Angeles an 83% win probability and Arizona 19%, making the Chargers the largest favorite on the board. The matchup has produced approximately $12.1K across 292 trades.
Jacksonville is next. The Browns-Jaguars market prices the Jaguars at 79% and Cleveland at 22%, with approximately $2.9K traded across 237 trades.
Sunday and Monday night markets
Dallas is priced at 61% against the Giants' 41% in the Sunday night matchup, which has generated approximately $14.4K across 620 trades. Kansas City is at 56% against Denver's 45% on Monday night, with approximately $7.2K across 351 trades.
Those primetime markets sit behind the opening-night and Thursday matchups in activity, but they remain among the strongest signals on the slate as Week 1 approaches.
What to watch before Week 1
Late injury designations, first-team availability and depth-chart changes are the most important inputs before Sept. 9. Not every roster update will move a prediction market. The live Week 1 board makes that distinction visible: follow the team news, then check whether traders materially change the matchup price.
Readers can also follow the broader league news cycle through AllTop Sports.